Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (2): 129-132.doi: 10.3760/cma.j.issn.1673422X.2017.02.013

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Novel drug targets in radiosensitivity of neoplasms

Wang Yanjun, Jiang Yongxin, Liu Shan, Wang Hong   

  1. Department of Teaching Management, Third Affiliated Hospital of Kunming Medical University; Tumor Clinical Research Center Combined Traditional Chinese and Western Medicine, Kunming 650118, China
  • Online:2017-02-08 Published:2017-01-04
  • Contact: Jiang Yongxin E-mail:598104374@qq.com

Abstract: Recent studies find a number of promising drug targets which can be applied for increasing tumor radiosensitivity in addition to normal tissue radioprotection, including oxygen free radical scavenger, drug targets in view of DNA damage repair and cell cycle, new targets inhibiting cell death, radioprotection mediated by growth factors, regulation of the cell signaling pathways, angiotensinconverting enzyme inhibitor, radiorestorative chemicals and so on.

Key words: Neoplasms, Radiotherapy, Radiationsensitizing agents