Journal of International Oncology ›› 2025, Vol. 52 ›› Issue (3): 136-143.doi: 10.3760/cma.j.cn371439-20241021-00021
• Original Article • Previous Articles Next Articles
Received:
2024-10-21
Revised:
2024-12-19
Online:
2025-03-08
Published:
2025-04-02
Contact:
Email:1527698862@qq.com
Han Shuang. CT feature analysis and predictive value of visceral pleural invasion in stage Ⅰ lung adenocarcinoma with peripheral solid nodules[J]. Journal of International Oncology, 2025, 52(3): 136-143.
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项目 | 训练集(n=112) | 验证集(n=38) | t/χ2值 | P值 | 项目 | 训练集(n=112) | 验证集(n=38) | t/χ2值 | P值 |
---|---|---|---|---|---|---|---|---|---|
年龄(岁) | 60.30±10.19 | 59.52±9.69 | 0.41 | 0.680 | 钙化 | ||||
性别 | 有 | 6 | 5 | 1.52 | 0.217 | ||||
男 | 44 | 20 | 2.07 | 0.151 | 无 | 106 | 33 | ||
女 | 68 | 18 | 瘤内坏死 | ||||||
病理类型 | 有 | 31 | 8 | 0.65 | 0.421 | ||||
AIS | 20 | 6 | 0.16 | 0.921 | 无 | 81 | 30 | ||
MIA | 18 | 7 | 空泡征 | ||||||
IA | 74 | 25 | 有 | 27 | 4 | 3.19 | 0.074 | ||
病灶分布 | 无 | 85 | 34 | ||||||
右肺 | 70 | 24 | 0.01 | 0.942 | 空气支气管征 | ||||
左肺上叶 | 42 | 14 | 有 | 31 | 12 | 0.21 | 0.646 | ||
VPI | 无 | 81 | 26 | ||||||
阳性 | 35 | 12 | <0.01 | 0.970 | 周围性肺气肿 | ||||
阴性 | 77 | 26 | 有 | 11 | 7 | 1.26 | 0.262 | ||
病灶最大径(cm) | 1.71±0.43 | 1.75±0.35 | 0.52 | 0.605 | 无 | 101 | 31 | ||
形态 | 外周纤维化 | ||||||||
规则 | 39 | 13 | 0.01 | 0.945 | 有 | 27 | 8 | 0.15 | 0.700 |
不规则 | 73 | 25 | 无 | 85 | 30 | ||||
边界 | 胸膜牵拉 | ||||||||
清晰 | 72 | 24 | 0.02 | 0.900 | 有 | 65 | 25 | 0.71 | 0.399 |
模糊 | 40 | 14 | 无 | 47 | 13 | ||||
分叶征 | 胸膜接触 | ||||||||
有 | 81 | 23 | 1.86 | 0.173 | 有 | 41 | 10 | 1.34 | 0.247 |
无 | 31 | 15 | 无 | 71 | 28 | ||||
毛刺征 | 邻近胸膜增厚 | ||||||||
有 | 63 | 22 | 0.03 | 0.860 | 有 | 38 | 13 | <0.01 | 0.975 |
无 | 49 | 16 | 无 | 74 | 25 | ||||
密度 | 淋巴结肿大 | ||||||||
实性 | 48 | 19 | 0.59 | 0.444 | 有 | 13 | 3 | 1.10 | 0.736 |
亚实性 | 64 | 19 | 无 | 99 | 35 | ||||
晕征 | |||||||||
有 | 53 | 20 | 0.32 | 0.571 | |||||
无 | 59 | 18 |
"
项目 | VPI阴性组(n=77) | VPI阳性组(n=35) | t/χ2值 | P值 | 项目 | VPI阴性组(n=77) | VPI阳性组(n=35) | t/χ2值 | P值 |
---|---|---|---|---|---|---|---|---|---|
年龄(岁) | 59.27±11.18 | 61.15±8.82 | 0.88 | 0.382 | 钙化 | ||||
性别 | 有 | 3 | 3 | 0.32 | 0.571 | ||||
男 | 27 | 17 | 1.84 | 0.175 | 无 | 74 | 32 | ||
女 | 50 | 18 | 瘤内坏死 | ||||||
病理类型 | 有 | 16 | 15 | 5.86 | 0.015 | ||||
AIS | 20 | 0 | 11.49 | 0.003 | 无 | 61 | 20 | ||
MIA | 10 | 8 | 空泡征 | ||||||
IA | 47 | 27 | 有 | 17 | 10 | 0.56 | 0.456 | ||
病灶分布 | 无 | 60 | 25 | ||||||
右肺 | 49 | 21 | 0.14 | 0.713 | 空气支气管征 | ||||
左肺 | 28 | 14 | 有 | 18 | 13 | 2.28 | 0.131 | ||
病灶最大径(cm) | 1.50±0.44 | 2.12±0.67 | 5.83 | <0.001 | 无 | 59 | 22 | ||
形态 | 周围性肺气肿 | ||||||||
规则 | 29 | 10 | 0.88 | 0.349 | 有 | 5 | 6 | 3.08 | 0.079 |
不规则 | 48 | 25 | 无 | 72 | 29 | ||||
边界 | 外周纤维化 | ||||||||
清晰 | 50 | 22 | 0.05 | 0.832 | 有 | 16 | 11 | 1.49 | 0.222 |
模糊 | 27 | 13 | 无 | 61 | 24 | ||||
分叶征 | 胸膜牵拉 | ||||||||
有 | 49 | 32 | 9.29 | 0.002 | 有 | 36 | 29 | 12.88 | <0.001 |
无 | 28 | 3 | 无 | 41 | 6 | ||||
毛刺征 | 胸膜接触 | ||||||||
有 | 39 | 24 | 3.14 | 0.076 | 有 | 23 | 18 | 4.82 | 0.028 |
无 | 38 | 11 | 无 | 54 | 17 | ||||
密度 | 邻近胸膜增厚 | ||||||||
实性 | 26 | 22 | 8.32 | 0.004 | 有 | 21 | 17 | 4.87 | 0.027 |
亚实性 | 51 | 13 | 无 | 56 | 18 | ||||
晕征 | 淋巴结肿大 | ||||||||
有 | 33 | 20 | 1.97 | 0.160 | 有 | 8 | 5 | 0.08 | 0.781 |
无 | 44 | 15 | 无 | 69 | 30 |
"
项目 | 单因素 | 多因素 | |||||
---|---|---|---|---|---|---|---|
OR值 | 95%CI | P值 | OR值 | 95%CI | P值 | ||
病理类型 | |||||||
IA | Ref | ||||||
AIS | 1.21 | 0.44~3.31 | 0.350 | ||||
MIA | 1.02 | 0.97~1.05 | 0.685 | ||||
病灶最大径 | 1.48 | 1.09~2.01 | 0.010 | 1.94 | 0.33~3.18 | 0.151 | |
分叶征 | |||||||
无 | Ref | ||||||
有 | 5.09 | 2.31~6.00 | 0.001 | 6.42 | 1.42~18.58 | 0.018 | |
密度 | |||||||
亚实性 | Ref | ||||||
实性 | 4.25 | 1.47~7.18 | 0.004 | 0.74 | 0.23~2.33 | 0.930 | |
瘤内坏死 | |||||||
无 | Ref | ||||||
有 | 2.27 | 1.01~5.17 | 0.049 | 3.63 | 1.01~10.01 | 0.046 | |
胸膜牵拉 | |||||||
无 | Ref | ||||||
有 | 6.75 | 1.92~13.68 | <0.001 | 4.19 | 1.17~10.92 | 0.028 | |
胸膜接触 | |||||||
无 | Ref | ||||||
有 | 3.58 | 1.18~5.65 | 0.018 | 1.02 | 0.32~3.22 | 0.607 | |
邻近胸膜增厚 | |||||||
无 | Ref | ||||||
有 | 3.60 | 1.18~5.72 | 0.018 | 0.73 | 0.48~1.12 | 0.954 | |
影像组学评分 | 19 418.06 | 394.18~957 161.04 | <0.001 | 179 711.20 | 525.13~61 552 573.59 | <0.001 |
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