Journal of International Oncology ›› 2023, Vol. 50 ›› Issue (2): 107-111.doi: 10.3760/cma.j.cn371439-20220726-00022

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Application of CT-based radiomics analysis in predicting and identifying of treatment-associated pneumonitis

Cao Xiaohui1, Yu Hong2, Li Wanhu3()   

  1. 1Department of Oncology,Third Hospital of Hebei Medical University,Shijiazhuang 050051,China
    2Department of Radiology,Third Hospital of Hebei Medical University,Shijiazhuang 050051,China
    3Department of Radiology,Shandong Cancer Hospital and Institute,Shandong First Medical University and Shandong Academy of Medical Sciences,Jinan 250117,China
  • Received:2022-07-26 Revised:2022-09-20 Online:2023-02-08 Published:2023-03-22
  • Contact: Li Wanhu,Email:lwhvzg@126.com<
  • Supported by:
    Shandong Cancer Hospital and Institute Clinical Research Cultivation Project(2020-19);Roentgen Imaging Research Project of Beijing Kangmeng Charity Foundation(SD-202008-017)

Abstract:

As a non-invasive image analysis method,radiomics can deeply explore the clinical information hidden behind medical images,and has been widely used in medicine in recent years. Consolidation immunotherapy after concurrent chemoradiotherapy has become the standard treatment for locally advanced non-small cell lung cancer. The prediction and identification of treatment-associated adverse events radiation pneumonitis (RP) and immune checkpoint inhibitor-related pneumonitis (CIP) are of vital importance for the formulation of treatment plan and the selection of subsequent treatment. CT-based radiomics analysis shows great potential in predicting and identifying RP and CIP.

Key words: Radiomics, Radiation pneumonitis, Immune checkpoint inhibitor-related pneumonitis, Precision radiotherapy