Journal of International Oncology ›› 2020, Vol. 47 ›› Issue (9): 555-559.doi: 10.3760/cma.j.cn371439-20200423-00077

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Radiogenomics in non-small cell lung cancer

Yang Lei, Zhang Chuanyu(), Zhang Zaixian, Liu Huan   

  1. Department of Radiology, Affiliated Hospital of Qingdao University, Qingdao 266000, China
  • Received:2020-04-23 Revised:2020-07-25 Online:2020-09-08 Published:2020-10-27
  • Contact: Zhang Chuanyu E-mail:zhangchuanyu0926@163.com

Abstract:

Radiogenomics explores the relationship between imaging features and gene expression patterns using radiomics, which is non-invasive and can present the overall information of tumors. The application of radiomics, somewhat effective in predicting gene mutations in non-small cell lung cancer (NSCLC), has recently become a research focus. Radiomic features, combined with conventional imaging, clinical and other features, can provide multi-directional information on tumors and play an increasingly important role in the prediction and precise treatment of NSCLC-driving gene phenotypes.

Key words: Carcinoma,non-small-cell lung, Receptor,epidermal growth factor, Anaplastic lymphoma kinase, KRAS gene, Radiomics