Journal of International Oncology ›› 2023, Vol. 50 ›› Issue (10): 627-630.doi: 10.3760/cma.j.cn371439-20230616-00119

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SPRY4-IT1 and breast cancer

Yan Xuemin1, Wu Xiaoyong2, Zhang Jiayi2, Wen Jinxu2, Wang Yuexin2()   

  1. 1Graduate School of North China University of Science and Technology, Tangshan 063000, China
    2Department of Gland Surgery, Hebei General Hospital, Shijiazhuang 050000, China
  • Received:2023-06-16 Revised:2023-09-07 Online:2023-10-08 Published:2023-11-08
  • Contact: Wang Yuexin E-mail:wangyx886@sina.com

Abstract:

Long non-coding RNA (lncRNA) is an RNA molecule that does not code to express proteins, and plays an important role in the occurrence and development of a variety of tumors. As an lncRNA, SPRY4-IT1 is highly expressed in breast cancer tissues, and can be used as an upstream and downstream regulator of breast cancer, promoting the progression of breast cancer, and is closely related to breast cancer stage and prognosis. In-depth study of the molecular mechanism associated with SPRY4-IT1 and breast cancer can provide new ideas for discovering biomarkers for early diagnosis of breast cancer, assessing disease prognosis and finding targeting sites.

Key words: RNA, long noncoding, Breast neoplasms, SPRY4-IT1