Journal of International Oncology ›› 2023, Vol. 50 ›› Issue (9): 540-543.doi: 10.3760/cma.j.cn371439-20230506-00103

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Role of linc01410 in the occurrence and development of malignant tumors

Liu Yang1, Jiang Lulu2, Guan Kaiwen1, Zhou Yueyang1, Kang Xiaohong1()   

  1. 1Department of Oncology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453000, China
    2Department of Orthopedics, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453000, China
  • Received:2023-05-06 Revised:2023-05-23 Online:2023-09-08 Published:2023-10-26
  • Contact: Kang Xiaohong E-mail:kxhhgd@163.com
  • Supported by:
    National Natural Science Foundation of China(81874392);National Natural Science Foundation of China(82074231);Science and Technology Development Program of Henan Province of China(212102310209);Key Project of Medical Science and Technology of Henan Province of China(SB201903014);Overseas Training Project of Health Science and Technology Talents of Henan Province of China(HWYX2019085)

Abstract:

Long non-coding RNA (lncRNA) is a class of highly conserved transcript with a length of more than 200 nucleotides, which is of great significance for the occurrence, development, diagnosis and treatment of malignant tumors. The abnormal expression of linc01410 in malignant tumors can affect the occurrence and development of malignant tumors by regulating the biological processes such as proliferation, migration and epithelial-mesenchymal transformation of malignant tumor cells, acting on related signaling pathways such as nuclear factor-κB and Notch or through exosome pathways.

Key words: Neoplasms, RNA, long noncoding