Diagnosis, treatment and prognosis of human major exocrine ductal carcinoma

doi:10.3760/cma.j.cn371439-20210602-00087

Abstract

Abstract:

Exocrine ductal carcinoma is an important part of malignant tumors of exocrine glands, including invasive breast ductal carcinoma, salivary duct carcinoma, pancreatic ductal adenocarcinoma and cholangiocarcinoma. Most of these diseases are aggressive, highly malignant and endanger human health. Early detection and diagnosis are the key to a good prognosis for exocrine ductal carcinoma. Different exocrine ductal carcinomas also have certain connections, and their molecular biological characteristics, pathological characteristics and molecular mechanisms have similarities. Surgical resection combined with adjuvant radiotherapy and chemotherapy is currently a common treatment method for exocrine ductal carcinoma. At the same time, its related targeted therapy and immunotherapy sites can also learn from each other. Human epidermal growth factor receptor-2 (HER-2) and the family markers have become breast ductal carcinoma and salivary duct carcinoma targeted therapy sites, and immunotherapy at programmed death ligand 1 (PD-L1) sites has also been involved in many studies, but there is no clear conclusion yet.

Key words: Ductal carcinoma, Diagnose, Molecular targeted therapy, Prognosis

Ma Pingchuan, Li Chunjie, Li Longjiang. Diagnosis, treatment and prognosis of human major exocrine ductal carcinoma[J]. Journal of International Oncology, 2021, 48(8): 449-455.

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