Journal of International Oncology ›› 2021, Vol. 48 ›› Issue (8): 456-462.doi: 10.3760/cma.j.cn371439-20210520-00088
Previous Articles Next Articles
Received:2021-05-20
Revised:2021-06-30
Online:2021-08-08
Published:2021-09-08
"
"
"
"
| 串联器官 | 体积 (cm3) | 体积最大 剂量(Gy) | 最大点 剂量(Gy) | 不良事件 (≥3级) |
|---|---|---|---|---|
| 脑 | <10 | 12 | - | 放射性脑坏死 |
| <31a | 5 | - | ||
| 视觉通路 | <0.2 | 8 | 10 | 神经炎 |
| 晶体 | 10 | 白内障 | ||
| 耳蜗 | 9 | 听力减退 | ||
| 脑干(非脊髓) | <0.5 | 10 | 15 | 颅神经病变 |
| 脊髓 | <1.2 | 7 | 14 | 脊髓炎 |
| 脊髓分段(上下 各5~6 mm) | <0.35 | 10 | 14 | 脊髓炎 |
| 马尾 | <5 | 14 | 16 | 神经炎 |
| 骶丛神经 | <5 | 14.4 | 16 | 神经病变 |
| 海马b | Dmean<3 | Dmax<9 |
"
| 串联器官 | 体积(cm3) | 体积最大剂量 | 最大点剂量 | 不良事件(≥3级) |
|---|---|---|---|---|
| 视觉通路 | <0.2 | 15.3 Gy(5.1 Gy/Fx) | 17.4 Gy(5.8 Gy/Fx) | 神经炎 |
| 耳蜗 | 17.1 Gy(5.7 Gy/Fx) | 听力减退 | ||
| 脑干(非脊髓) | <0.5 | 18 Gy(6 Gy/Fx) | 23.1 Gy(7.7 Gy/Fx) | 颅神经病变 |
| 脊髓 | <1.2 | 12.3 Gy(4.1 Gy/Fx) | 脊髓炎 | |
| 脊髓分段(上下各5~6 mm) | <0.35 | 18 Gy(6 Gy/Fx) | 21.9 Gy(7.3 Gy/Fx) | 脊髓炎 |
| 马尾 | <5 | 21.9 Gy(7.3 Gy/Fx) | 24 Gy(8 Gy/Fx) | 神经炎 |
| 骶丛神经 | <5 | 22.5 Gy(7.5 Gy/Fx) | 24 Gy(8 Gy/Fx) | 神经病变 |
"
| 串联器官 | 体积(cm3) | 体积最大剂量 | 最大点剂量 | 不良事件(≥3级) |
|---|---|---|---|---|
| 视觉通路 | <0.2 | 23 Gy(4.6Gy/Fx) | 25 Gy(5 Gy/Fx) | 神经炎 |
| 耳蜗 | 25 Gy(5 Gy/Fx) | 听力减退 | ||
| 脑干(非脊髓) | <0.5 | 23 Gy(4.6 Gy/Fx) | 31 Gy(6.2 Gy/Fx) | 颅神经病变 |
| 脊髓 | <1.2 | 14.5 Gy(2.9 Gy/Fx) | 脊髓炎 | |
| 脊髓分段(上下各5~6 mm) | <0.35 | 23 Gy(4.6 Gy/Fx) | 30 Gy(6 Gy/Fx) | 脊髓炎 |
| 马尾 | <5 | 30 Gy(6 Gy/Fx) | 32 Gy(6.4 Gy/Fx) | 神经炎 |
| 骶丛神经 | <5 | 30 Gy(6 Gy/Fx) | 32 Gy(6.4 Gy/Fx) | 神经病变 |
"
"
"
"
"
| [1] |
Schouten LJ, Rutten J, Huveneers H, et al. Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma[J]. Cancer, 2002,94(10):2698-2705. DOI: 10.1002/cncr.10541.
doi: 10.1002/cncr.10541 pmid: 12173339 |
| [2] |
Parrish KE, Sarkaria JN, Elmquist WF. Improving drug delivery to primary and metastatic brain tumors: strategies to overcome the blood-brain barrier[J]. Clin Pharmacol Ther, 2015,97(4):336-346. DOI: 10.1002/cpt.71.
doi: 10.1002/cpt.71 pmid: 25669487 |
| [3] |
Chang EL, Wefel JS, Hess KR, et al. Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial[J]. Lancet Oncol, 2009,10(11):1037-1044. DOI: 10.1016/S1470-2045(09)70263-3.
doi: 10.1016/S1470-2045(09)70263-3 pmid: 19801201 |
| [4] |
Kocher M, Wittig A, Piroth MD, et al. Stereotactic radiosurgery for treatment of brain metastases. A report of the DEGRO Working Group on Stereotactic Radiotherapy[J]. Strahlenther Onkol, 2014,190(6):521-532. DOI: 10.1007/s00066-014-0648-7.
doi: 10.1007/s00066-014-0648-7 |
| [5] |
Chao ST, De Salles A, Hayashi M, et al. Stereotactic radiosurgery in the management of limited (1-4) brain metasteses: systematic review and International Stereotactic Radiosurgery Society Practice Guideline[J]. Neurosurgery, 2018,83(3):345-353. DOI: 10.1093/neuros/nyx522.
doi: 10.1093/neuros/nyx522 |
| [6] |
Soffietti R, Abacioglu U, Baumert B, et al. Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO)[J]. Neuro Oncol, 2017,19(2):162-174. DOI: 10.1093/neuonc/now241.
doi: 10.1093/neuonc/now241 |
| [7] |
Seung SK, Larson DA, Galvin JM, et al. American College of Radiology (ACR) and American Society for Radiation Oncology (ASTRO) Practice Guideline for the performance of stereotactic radiosurgery (SRS)[J]. Am J Clin Oncol, 2013,36(3):310-315. DOI: 10.1097/COC.0b013e31826e053d.
doi: 10.1097/COC.0b013e31826e053d |
| [8] |
中国医师协会肿瘤医师分会. 中国肺癌脑转移诊治专家共识(2017年版)[J]. 中国肺癌杂志, 2017,20(1):1-13. DOI: 10.3779/j.issn.1009-3419.2017.01.01.
doi: 10.3779/j.issn.1009-3419.2017.01.01 |
| [9] |
Yamamoto M, Serizawa T, Shuto T, et al. Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study[J]. Lancet Oncol, 2014,15(4):387-395. DOI: 10.1016/S1470-2045(14)70061-0.
doi: 10.1016/S1470-2045(14)70061-0 pmid: 24621620 |
| [10] |
Eaton DJ, Lee J, Paddick I. Stereotactic radiosurgery for multiple brain metastases: results of multicenter benchmark planning studies[J]. Pract Radiat Oncol, 2018,8(4):e212-e220. DOI: 10.1016/j.prro.2017.12.011.
doi: 10.1016/j.prro.2017.12.011 |
| [11] |
戴建荣. 医用电子直线加速器质量控制指南[J]. 中华放射肿瘤学杂志, 2020,29(4):241-258. DOI: 10.3760/cma.j.cn113030-20200212-00001.
doi: 10.3760/cma.j.cn113030-20200212-00001 |
| [12] |
Danieli L, Riccitelli GC, Distefano D, et al. Brain tumor-enhancement visualization and morphometric assessment: a comparison of MPRAGE, SPACE, and VIBE MRI Techniques[J]. AJNR Am J Neuroradiol, 2019,40(7):1140-1148. DOI: 10.3174/ajnr.A6096.
doi: 10.3174/ajnr.A6096 |
| [13] |
Putz F, Mengling V, Perrin R, et al. Magnetic resonance imaging for brain stereotactic radiotherapy : a review of requirements and pitfalls[J]. Strahlenther Onkol, 2020,196(5):444-456. DOI: 10.1007/s00066-020-01604-0.
doi: 10.1007/s00066-020-01604-0 |
| [14] |
Soliman H, Ruschin M, Angelov L, et al. Consensus contouring guidelines for postoperative completely resected cavity stereotactic radiosurgery for brain metastases[J]. Int J Radiat Oncol Biol Phys, 2018,100(2):436-442. DOI: 10.1016/j.ijrobp.2017.09.047.
doi: 10.1016/j.ijrobp.2017.09.047 |
| [15] |
Baumert BG, Rutten I, Dehing-Oberije C, et al. A pathology-based substrate for target definition in radiosurgery of brain metastases[J]. Int J Radiat Oncol Biol Phys, 2006,66(1):187-194. DOI: 10.1016/j.ijrobp.2006.03.050.
doi: 10.1016/j.ijrobp.2006.03.050 |
| [16] |
Shaw E, Scott C, Souhami L, et al. Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: final report of RTOG protocol 90-05[J]. Int J Radiat Oncol Biol Phys, 2000,47(2):291-298. DOI: 10.1016/s0360-3016(99)00507-6.
doi: 10.1016/s0360-3016(99)00507-6 |
| [17] |
Kim KH, Kong DS, Cho KR, et al. Outcome evaluation of patients treated with fractionated Gamma Knife radiosurgery for large (>3 cm) brain metastases: a dose-escalation study[J]. J Neurosurg, 2019,16:1-10. DOI: 10.3171/2019.5.JNS19222.
doi: 10.3171/2019.5.JNS19222 |
| [18] |
Minniti G, Scaringi C, Paolini S, et al. Single-fraction versus multifraction (3 × 9 Gy) stereotactic radiosurgery for large (>2 cm) brain metastases: a comparative analysis of local control and risk of radiation-induced brain necrosis[J]. Int J Radiat Oncol Biol Phys, 2016,95(4):1142-1148. DOI: 10.1016/j.ijrobp.2016.03.013.
doi: 10.1016/j.ijrobp.2016.03.013 |
| [19] |
Remick JS, Kowalski E, Khairnar R, et al. A multi-center analysis of single-fraction versus hypofractionated stereotactic radiosurgery for the treatment of brain metastasis[J]. Radiat Oncol, 2020,15(1):128. DOI: 10.1186/s13014-020-01522-6.
doi: 10.1186/s13014-020-01522-6 pmid: 32466775 |
| [20] |
Brown PD, Ballman KV, Cerhan JH, et al. Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC·3): a multicentre, randomised, controlled, phase 3 trial[J]. Lancet Oncol, 2017,18(8):1049-1060. DOI: 10.1016/ S1470-2045(17) 30441-2.
doi: S1470-2045(17)30441-2 pmid: 28687377 |
| [21] |
Fiorentino A, Tebano U, Sicignano G, et al. Hippocampal dose during Linac-based stereotactic radiotherapy for brain metastases: an observational study[J]. Phys Med, 2018,49:135-138. DOI: 10.1016/j.ejmp.2017.09.129.
doi: S1120-1797(17)30452-0 pmid: 28951047 |
| [22] |
Ali FS, Arevalo O, Zorofchian S, et al. Cerebral radiation necrosis: incidence, pathogenesis, diagnostic challenges, and future opportunities[J]. Curr Oncol Rep, 2019,21(8):66. DOI: 10.1007/s11912-019-0818-y.
doi: 10.1007/s11912-019-0818-y |
| [23] |
Bodensohn R, Hadi I, Fleischmann DF, et al. Bevacizumab as a treatment option for radiation necrosis after cranial radiation therapy: a retrospective monocentric analysis[J]. Strahlenther Onkol, 2020,196(1):70-76. DOI: 10.1007/s00066-019-01521-x.
doi: 10.1007/s00066-019-01521-x pmid: 31586230 |
| No related articles found! |
| Viewed | ||||||
|
Full text |
|
|||||
|
Abstract |
|
|||||
