Clinical significance of exosomal-circRNA in tumor diagnosis and treatment

doi:10.3760/cma.j.cn371439-20210206-00106

Abstract

Abstract:

There are abundant and stable circular RNAs in tumor-derived exosomes, which play an important role in the occurrences and developments of tumors. Exosome-circRNAs can be used as the marker of tumors diagnosis and prognosis, and have different roles in regulating tumors immune responses, regulating tumors progressions and mediating tumors drug resistances in different tumors. Exploring and applying the potential value of exosome-circRNAs will provide a new choice for the diagnosis and treatment of tumors.

Key words: Exosomes, Neoplasms, Circular RNA

Zhang Wanchen, Xu Jiajie, Zhang Lizhuo, Ge Minghua. Clinical significance of exosomal-circRNA in tumor diagnosis and treatment[J]. Journal of International Oncology, 2021, 48(9): 549-552.

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