国际肿瘤学杂志

国际肿瘤学杂志 ›› 2017, Vol. 44 ›› Issue (8): 597-600.doi: 10.3760/cma.j.issn.1673-422X.2017.08.010

• 综述 • 上一篇    下一篇

基于MRI图像纹理分析肿瘤异质性的临床应用

陶恒敏,魏玉梅,钱明   

  1. 济南，山东大学附属省立医院头颈放疗科（陶恒敏、钱明）；山东大学附属山东省肿瘤医院放疗六病区（魏玉梅）
  • 出版日期:2017-08-08 发布日期:2017-07-21
  • 通讯作者: 钱明，Email: sdqianming@163.com E-mail:sdqianming@163.com
  • 基金资助:

    山东省医药卫生科技发展计划（2015WS0158）

Clinical application of tumor heterogeneity based on MRI texture analysis

Tao Hengmin, Wei Yumei, Qian Ming   

  1. Department of Head and Neck Radiotherapy, Shandong Provincial Hospital Affiliated to Shandong University, Ji′nan 250022, China
  • Online:2017-08-08 Published:2017-07-21
  • Contact: Qian Ming, Email: sdqianming@163.com E-mail:sdqianming@163.com
  • Supported by:

    Medical and Health Research Project of Shandong Province of China (2015WS0158)

PDF

1304

摘要： 恶性肿瘤的一个普遍特征是生物异质性。MRI纹理分析（MTA）是一项新的图像后处理技术，可作为量化病灶异质性的工具。越来越多的研究显示MTA在肿瘤成像上是一项具有潜力的技术，能为临床诊疗提供很多重要的、有价值的信息，包括肿瘤的特征分析、预后判断以及肿瘤治疗反应的预测与监测等。本文通过对MTA在评估肿瘤异质性及其临床应用的文献进行综述，总结MTA与放化疗反应、预后、生存期的关系以及作为影像学标志物在肿瘤临床中的作用，以便进一步探讨其在临床应用中的潜能。

关键词: 肿瘤, 遗传异质性, 磁共振成像, 纹理分析

Abstract: Heterogeneity is one of the important features of malignant tumors. MRI texture analysis (MTA) is a new imaging postprocessing technique to quantify heterogeneity of tumor. Increasing number of studies have shown that MTA is a potentially useful tool in tumor imaging, and can provide important and valuable information including tumor characteristics, prognosis assessment, prediction or monitoring of tumor treatment response, and so on. In this article, we review the literatures about MTA in evaluating heterogeneity of tumor. The correlation between MTA and tumor response to chemotherapy, prognosis and survival time, and the role of MTA as imaging markers in clinical practice are summarized, to further explore its potential in clinical application.

Key words: Neoplasms, Genetic heterogeneity, Magnetic resonance imaging, Texture analysis