新作用机制的抗肿瘤药物进展

doi:10.3760/cma.j.cn371439-20240318-00061

摘要/Abstract

摘要：

细胞毒性药物、分子靶向药物和免疫检查点抑制剂构成了目前肿瘤系统治疗的基本模式，新作用机制的抗肿瘤药物，包括激酶抑制剂、治疗性抗体、核酸阻断剂、治疗性疫苗、基因编辑免疫细胞、微型机器人和数字药物将改变现有的治疗模式。靶向神经、多糖、脂质和菌群的药物可能逐步进入肿瘤临床。

关键词: 肿瘤, 抗肿瘤药, 治疗

Abstract:

Cytotoxic agents， molecular targeted agents and immune checkpoint inhibitors consist of the fundamental model of cancer systematic treatments. Anti-tumor drugs with new mechanisms of action， including kinase inhibitors， therapeutic antibodies， nucleic acid blocks， therapeutic vaccines， gene-edited immune cells， living microrobots and digital drugs， will change this existing model. Drugs targrting nerves， polysaccharides， lipids and microflora may gradually enter clinical applications.

Key words: Neoplasms, Antineoplastic agents, Therapy

张百红, 岳红云. 新作用机制的抗肿瘤药物进展[J]. 国际肿瘤学杂志, 2024, 51(6): 354-358.

Zhang Baihong, Yue Hongyun. Advances in anti-tumor drugs with new mechanisms of action[J]. Journal of International Oncology, 2024, 51(6): 354-358.

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