国际肿瘤学杂志 ›› 2017, Vol. 44 ›› Issue (12): 907-910.doi: 10.3760/cma.j.issn.1673-422X.2017.12.006

• 论著 • 上一篇    下一篇

改良13点前列腺穿刺活检在前列腺癌 诊断中的应用

申骏龙,刘全海,刘莉,南淑良,程永毅,周建成   

  1. 710068 西安,陕西省人民医院泌尿外科病院(申骏龙、刘全海、程永毅、周建成),超声诊断中心(刘莉、 南淑良)
  • 出版日期:2017-12-08 发布日期:2017-12-01
  • 通讯作者: 周建成,Email: 26675085@163.com E-mail: 26675085@163.com
  • 基金资助:
    国家自然科学基金(81602237)

Application of improved 13-core prostate biopsy in the diagnosis of prostate cancer

Shen Junlong, Liu Quanhai, Liu Li, Nan Shuliang, Cheng Yongyi, Zhou Jiancheng.   

  1. Department of Urology, Shaanxi Provincial People′s Hospital, Xi′an 710068, China
  • Online:2017-12-08 Published:2017-12-01
  • Contact: Zhou Jiancheng, Email: 26675085@163.com E-mail: 26675085@163.com
  • Supported by:
    National Natural Science Foundation of China (81602237)

摘要: 目的评价经直肠超声引导改良13点前列腺穿刺活检对诊断前列腺癌的临床价值。方法对2015年10月至2016年10月在陕西省人民医院就诊的82例临床疑似前列腺癌患者的临床资料进行回顾性分析。所有患者均进行了经直肠超声引导改良13点前列腺穿刺活检及手术治疗,将穿刺病理结果与术后病理结果进行比较,并比较改良13点穿刺法和标准6点穿刺法诊断前列腺癌的准确性,分析改良13点前列腺穿刺活检术的并发症。结果82例疑似前列腺癌患者中,26例经直肠超声引导下改良13点前列腺穿刺术诊断为前列腺癌,54例诊断为前列腺增生,此80例诊断结果与术后病理相符,另2例穿刺活检诊断为前列腺增生而术后病理证实为前列腺癌。改良13点穿刺法和标准6点穿刺法诊断前列腺癌的准确性分别为97.6%(80/82)和84.1%(69/82),两者比较差异有统计学意义(P=0.023)。所有接受改良13点法前列腺穿刺活检术的患者无一例出现严重的并发症。结论经直肠超声引导改良13点前列腺穿刺活检术是一种安全、有效的前列腺系统穿刺活检术式,值得在临床推广应用。

关键词: 前列腺肿瘤, 活组织检查, 诊断

Abstract: ObjectiveTo investigate the clinical value of transrectal ultrasound-guided improved 13-core prostate biopsy in the detection of prostate cancer. MethodsRetrospective analysis was conducted in the clinical data of 82 clinically suspected prostate cancer patients in Shaanxi Provincial People′s Hospital from October 2015 to October 2016. All patients were undergone transrectal ultrasound-guided improved 13-core prostate biopsy and surgical treatment, and the prostate biopsy results were compared with the postoperative pathological results. The accuracy of the improved 13-core prostate biopsy and the standard 6-core prostate biopsy was compared. The complications of improved 13-core prostate biopsy were also discussed. ResultsThe diagnostic results of prostate biopsy included prostate cancer in 26 patients and benign prostatic hyperplasia (BPH) in 54 patients. The diagnostic results of 80 patients are consistent with postoperative pathological examination. Two patients were diagnosed as BPH by biopsy, but confirmed to be prostate cancer by postoperative pathological examination. The accuracy of the improved 13-core prostate biopsy and the standard 6-core prostate biopsy were 97.6% (80/82) and 84.1% (69/82) respectively, and the difference showed statistical significance (P=0.023). No severe complications were found in patients who underwent transrectal ultrasound improved 13-core prostate biopsy. ConclusionTransrectal ultrasound guided improved 13-core prostate biopsy can increase the detection rate significantly. It is safe and efficacious, and can be widely used in clinic.

Key words: Prostatic neoplasms, Biopsy, Diagnosis