国际肿瘤学杂志 ›› 2016, Vol. 43 ›› Issue (2): 145-.

• 综述 • 上一篇    下一篇

鼻咽癌放疗相关第二原发口腔癌的研究进展

赵楠, 吴桐, 程斌   

  1. 中山大学光华口腔医学院附属口腔医院黏膜科
  • 出版日期:2016-02-08 发布日期:2015-12-28

Research advances on second primary malignancies of oral cavity following radiotherapy for nasopharyngeal carcinoma

ZHAO  Nan, WU  Tong, CHENG  Bin   

  1. Department of Oral Medicine, Guanghua School of Stomatology, Sun Yatsen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China
  • Online:2016-02-08 Published:2015-12-28

摘要: 放疗作为鼻咽癌(NPC)的主要治疗方法已使其得到有效控制,但由于与鼻咽部解剖位置临近,放疗引起的口腔并发症非常普遍,口腔第二原发癌(SPM)已成为导致NPC患者最终生存率低的重要原因。SPM的发病机制尚未完全明确,患者预后较差,对其的研究仍在探索中。

关键词: 鼻咽肿瘤, 放射疗法, 口腔, 第二原发癌

Abstract: Radiotherapy is the primary treatment modality for nasopharyngeal carcinoma(NPC) which can effectively control the disease. Oral cavity, anatomically near nasopharyngeal region is the main area for the occurrence of complication of radiotherapy. Second primary malignancy (SPM) in oral cavity is an important factor interferencing NPC patients survival rate. The etiology of oral SPM is unclear and, the prognosis is poor. The research of it is still in exploration.

Key words: Nasopharyngeal neoplasms, Radiotherapy, Mouth, Second primary malignancies