国际肿瘤学杂志

国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (7): 491-493.

• 综述 • 上一篇    下一篇

肾上腺髓质素对细胞迁移作用的研究进展  

支力强, 郭池华, 马巍   

  1. 710061西安交通大学第一附属医院骨科
  • 出版日期:2013-07-08 发布日期:2013-07-08
  • 通讯作者: 马巍 E-mail:mawei60@126.com

Research progress of adrenomedullin on cell migration activity

ZHI  Li-Qiang, GUO  Chi-Hua, MA  Wei-   

  1. Department of Orthopedics, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China
  • Online:2013-07-08 Published:2013-07-08
  • Contact: MA Wei E-mail:mawei60@126.com

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摘要： 肾上腺髓质素(ADM)在体内分布广泛，具有多种生物学效应，可参与体内多种生理、病理过程，且与肿瘤的恶性程度、预后、转移与否等均有密切联系。ADM对不同类型的细胞，可通过一种或多种途径影响细胞的迁移，并产生不同的效应。为预防或延缓肿瘤转移提供了新的治疗方向。

关键词: 肾上腺髓质素, 细胞运动, 内皮细胞, 肿瘤

Abstract: Adrenomedullin (ADM) has wide distribution in the body and has many biological effects, which participates in many physiological and pathological processes. What’s more, it is closely related to the degree of malignancy, prognosis and metastasis of tumors. ADM has different effects on different types of cells via one or more signal pathways, so that can product various effects. It also provides a new treatment strategy for preventing or slowing the progress of the cancer.

Key words: Adrenomedullin, Cell movement, Endothelial cells, Neoplasms