坏死性凋亡相关复合物与肿瘤

doi:10.3760/cma.j.issn.1673-422X.2018.10.010

国际肿瘤学杂志 ›› 2018, Vol. 45 ›› Issue (10): 624-626.doi: 10.3760/cma.j.issn.1673-422X.2018.10.010

坏死性凋亡相关复合物与肿瘤

丁金晔,程忠平

200072 同济大学附属上海市第十人民医院妇产科

收稿日期:2018-04-10 出版日期:2018-10-08 发布日期:2018-12-21
通讯作者: 程忠平 E-mail:mdcheng18@tongji.edu.cn

Complexities in necroptosis and tumor

Ding Jinye, Cheng Zhongping

Department of Gynecology and Obstetrics, Tenth People′s Hospital Affiliated to Tongji University, Shanghai 200072, China

Received:2018-04-10 Online:2018-10-08 Published:2018-12-21
Contact: Cheng Zhongping E-mail:mdcheng18@tongji.edu.cn

摘要/Abstract

摘要： 坏死性凋亡相关复合物是坏死性凋亡信号通路中的关键信号分子。它的形成受到坏死小体和坏死性凋亡小体等一系列因素的调控。研究发现，坏死性凋亡相关复合物与多种肿瘤密切相关，如胰腺导管腺癌、胶质瘤等。深入研究其调控机制有望为肿瘤分子治疗提供新思路。

关键词: 肿瘤, 坏死性凋亡相关复合物

Abstract: The complexities in necroptosis are pivotal signal molecules in the pathway. Its formation is regulated by a series of factors such as necrosome and ripoptosome. The studies have found that the complexities in necroptosis are closely related to multiple neoplasms, such as pancreatic ductal adenocarcinoma and glioma. Further study on the regulatory mechanism of them will provide a new idea for molecular cancer therapeutics.

Key words: Neoplasms, Complexities in necroptosis

丁金晔,程忠平. 坏死性凋亡相关复合物与肿瘤[J]. 国际肿瘤学杂志, 2018, 45(10): 624-626.

Ding Jinye, Cheng Zhongping. Complexities in necroptosis and tumor[J]. Journal of International Oncology, 2018, 45(10): 624-626.

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坏死性凋亡相关复合物与肿瘤

Complexities in necroptosis and tumor

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