国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (11): 833-836.doi: 10.3760/cma.j.issn.1673-422X.2014.11.011

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MMP-9与结直肠癌侵袭转移的相关性及临床研究进展

  

  1. 蚌埠医学院第一附属医院肿瘤外二科
  • 出版日期:2014-12-03 发布日期:2015-01-20
  • 通讯作者: 许培权,Email:xupeiquan2003@aliyun.com

Clinical research progress between MMP-9 and the invasion and metastasis of colorectal cancer

  1.  Second Department of Surgical Oncology, First Affiliated Hospital of Bengbu Medical College, Bengbu 233000, China
  • Online:2014-12-03 Published:2015-01-20
  • Contact: Xu Peiquan, Email: xupeiquan2003@aliyun.com

摘要: 基质金属蛋白酶(MMP)-9是MMP家族相对分子质量最大的MMP,主要来源于巨噬细胞和中性粒细胞,MMP9与结直肠癌的发生及侵袭转移相关,也可以为结直肠癌的临床预防及治疗提供新的途径

关键词: 基质金属蛋白酶9, 结直肠肿瘤, 肿瘤侵润, 肿瘤转移

Abstract: The molecular weight of matrix metalloproteinase (MMP)9 is the largest in MMP family which comes mainly from macrophage and neutrophil. MMP9 is considered to be involved in the occurrence and metastasis of colorectal cancer. It also provides a new way for colorectal cancer in clinical prevention and treatment.

Key words: Matrix metalloproteinase 9, Colorectal neoplasms, Neoplasm invasiveness, Neoplasm metastasis