人体组织中微生物群落与乳腺癌关系的研究进展

doi:10.3760/cma.j.cn371439-20240727-00132

摘要/Abstract

摘要：

乳腺癌作为女性发病率极高的恶性肿瘤，严重危害女性的生命健康与安全，其发病机制及治疗策略仍是目前研究的热点和难点。越来越多的研究表明，乳腺癌的发生发展与肠道组织、乳腺组织中的微生物群落密切相关，人体组织中的微生物群落可通过多种途径及机制促进或抑制乳腺癌的发生。明确微生物群落与乳腺癌的关系将为乳腺癌的预防和综合治疗提供新的方向。

关键词: 乳腺肿瘤, 微生物群落, 胃肠道微生物组, 鼠李糖乳杆菌

Abstract:

Breast cancer， as a malignant tumor with a high incidence rate in women， seriously endangers the life health and safety of women. Its pathogenesis and treatment strategies are still the hot and difficult points in current research. More and more studies have shown that the occurrence and development of breast cancer is closely related to the microbial community in intestinal tissue and breast tissue， and the microbial community in human tissue may promote or inhibit the occurrence of breast cancer through various ways and mechanisms. Defining the relationship between microbial communities and breast cancer will provide new directions for the prevention and comprehensive treatment of breast cancer.

Key words: Breast neoplasms, Microbial consortia, Gastrointestinal microbiome, Lactobacillus rhamnosus

周名睿, 戚孟琪, 张妍妍, 史易暖, 岳川, 张妍, 刘宪强, 张岩. 人体组织中微生物群落与乳腺癌关系的研究进展[J]. 国际肿瘤学杂志, 2024, 51(12): 779-784.

Zhou Mingrui, Qi Mengqi, Zhang Yanyan, Shi Yinuan, Yue Chuan, Zhang Yan, Liu Xianqiang, Zhang Yan. Research progress in the relationship between microbial communities and breast cancer in human tissues[J]. Journal of International Oncology, 2024, 51(12): 779-784.

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