肠道微生物群与血液肿瘤

doi:10.3760/cma.j.cn371439-20201019-00086

摘要/Abstract

摘要：

近年来宏基因组学测序技术研究发现,肠道微生物群的组成和多样性的变化与血液肿瘤的发生发展有关,肠道微生物群影响造血系统的发育,同时也影响血液肿瘤的预后分层。肠道微生物易位在血流感染中起着重要作用,肠道菌群失调和血流感染影响血液肿瘤的治疗效果,使用益生菌和粪菌移植可恢复肠道菌群的多样性。

关键词: 微生物群, 血液肿瘤, 治疗, 微生物群易位, 血流感染

Abstract:

In recent years, driven by metagenomics sequencing technology, it has been found that compositional changes and diversity changes of gut microbiota are related to the occurrence of hematological malignancies. Gut microbiota affects the development of the hematopoietic system and the risk stratification of hematological malignancies. Microbial translocation plays an important role in and blood stream infection. Gut microbiota imbalance and blood stream infection affect the therapeutic effect of hematological malignancies. Probiotics and fecal microbiota transplant can restore the diversity of gut microbiota.

Key words: Microbiota, Hematological neoplasms, Therapy, Microbial translocation, Blood stream infection

韦丽娅, 郭智. 肠道微生物群与血液肿瘤[J]. 国际肿瘤学杂志, 2021, 48(7): 445-448.

Wei Liya, Guo Zhi. Gut microbiota and hematological malignancies[J]. Journal of International Oncology, 2021, 48(7): 445-448.

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