SPINK1作为肿瘤标志物的临床价值与应用

doi:10.3760/cma.j.cn371439-20200216-00047

摘要/Abstract

摘要：

丝氨酸蛋白酶抑制剂因子Kazal 1型(SPINK1)是蛋白酶抑制剂家族成员之一,因其在卵巢癌、胰腺癌、肝细胞癌、结直肠癌、前列腺癌等恶性肿瘤发生、发展及预后中发挥重要作用,SPINK1作为一种肿瘤标志物的临床应用受到研究者广泛关注。

Abstract:

The serine protease inhibitor Kazal type 1 (SPINK1) is a member of the protease inhibitor family. As SPINK1 plays an essential role in the occurrence, development and prognosis of tumors, such as ovarian cancer,pancreatic cancer, hepatocellular carcinoma, colorectal cancer and prostate cancer, the clinical application of SPINK1 as a tumor marker has been widely concerned by researchers.

Key words: Serine protease inhibitors, Biomarkers, Neoplasms, Prognosis

赵娜, 郑洋, 陈丽丽, 荆东辉, 王华庆. SPINK1作为肿瘤标志物的临床价值与应用[J]. 国际肿瘤学杂志, 2020, 47(7): 414-418.

Zhao Na, Zheng Yang, Chen Lili, Jing Donghui, Wang Huaqing. Clinical value and application of SPINK1 as a tumor biomarker[J]. Journal of International Oncology, 2020, 47(7): 414-418.

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