Abstract: Accurate knowledge, diagnosis and treatment of breast ductal carcinoma in situ(DCIS), are crucial in controlling the development of breast cancer. In the diagnosis phase, breast ultrasound is commonly used as a screening tool, and a clear diagnosis can be made by mammography. Meanwhile, serological tests contribute to the detection of DCIS in early stages. In the treatment, the optimal surgical operation method remains debatable. It is widely acknowledged that the radiotherapy of postoperative patients should become more individualized. In addition, corresponding endocrine therapy helps those ER positive patients to reduce the recurrence. In the development of DCIS to invasive cancer, there are changes in gene and protein expressions, which may be a potential direction for further research.

Key words: Bresst neoplasms, Carcinoma, intraductal, noninfiltrating, Serologic tests, Therapy