Abstract: New oral fluoropyrimidines, such as capecitabine and S-1, have been widely used for elderly patients with a certain efficiency and slight toxicity. Fluorouracil and platinum program probably enhances the effectiveness, but also increases the incidence of adverse reactions. There are a few clinical reports about triple-drug combination for elderly patients, but the efficacy is not certain and the toxicity is obvious.

Key words: Stomach neoplasms, Aged, Chemotherapy, adjuvant