Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (10): 748-751.

Previous Articles     Next Articles

Application of attenuated salmonella in the gene treatment of tumor

LI  Peng-Fei, SUN  Jun-Zhong   

  1. Department of Oncology, First Affiliated Hospital of General Hospital of PLA, Beijing 100039, China

  • Online:2013-10-08 Published:2013-09-23
  • Contact: SUN Jun-zhong, E-mail: sjunzh07@163.com E-mail:sjunzh07@163.com

Abstract: Salmonella is a kind of intracellular invasive facultative anaerobe, maintaining its antigenicity after being attenuated. Now, it has been widely used as a  transporter of DNA vaccines. Salmonella carrying related antigen gene can inhibit multiple tumors, and salmonella carrying repair gene has a clear repair effect for the organism injury after chemoradiotherapy.

Key words: Attenuated salmonella, Neoplasms, Vaccine carrier, Damage repairment