Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (8): 595-597.

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EGFR mutation in malignant pleural effusion of non-small cell lung cancer

CHU  Hui-Li, LIANG  Xiu-Ju, BI  Jing-Wang   

  1. Department of Oncology, General Hospital, Jinan Command of the People’s Liberation Army, Jinan 250031, China
  • Online:2013-08-08 Published:2013-08-15
  • Contact: Corresponding author: BI Jing-wang, E-mail: jingwangbi@live.cn E-mail:jingwangbi@live.cn

Abstract: EGFR testing has become the consensus before EGFR-TKI treatment in non-small cell lung cancer patients. Malignant pleural effusion is the common clinical manifestation in NSCLC patients, and   EGFR testing by using different methods in pleural effusion cells and free nucleic acids has good prospect for predicting the efficacy of EGFR-TKI.

Key words: Carcinoma, non-small cell lung, Receptor, epidermal growth factor, Mutation, Malignant pleural effusion