Journal of International Oncology ›› 2022, Vol. 49 ›› Issue (3): 164-167.doi: 10.3760/cma.j.cn371439-20211025-00027

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NUF2 and tumor prognosis

Ren Meng1, Yang Lu2, Zhao Xiaoting1, Yue Wentao1()   

  1. 1Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing 100026, China
    2Beijing Etinpro Technologies Co.Ltd, Beijing 100023, China
  • Received:2021-10-25 Revised:2021-11-10 Online:2022-03-08 Published:2022-03-22
  • Contact: Yue Wentao E-mail:yuewt@ccmu.edu.cn
  • Supported by:
    Science & Technology Commission of Beijing Municipal of China(Z181100001718193)

Abstract:

NUF2 is responsible for the attachment of kinetochore-microtubules and proper chromosome segregation during mitosis. NUF2 is highly expressed in hepatocellular carcinoma, pancreatic cancer, esophageal cancer, non-small cell lung cancer, breast cancer and other tumor tissues and cells, and can be used as prognostic markers. Further clarifying the relationship between NUF2 and tumor prognosis can provide help for the application of NUF2 in prognostic assessment of cancers.

Key words: Neoplasms, Prognosis, NUF2