Journal of International Oncology ›› 2021, Vol. 48 ›› Issue (7): 429-432.doi: 10.3760/cma.j.cn371439-20200708-00082

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Research progress of immunotherapy in esophageal squamous cell carcinoma

Yang Wenqian1, Huang Junxing2()   

  1. 1Faculty of Clinical Medicine, Nantong University, Nantong 226000, China
    2Department of Oncology, Fifth Affiliated Hospital of Nantong University, Taizhou 225300, China
  • Received:2020-07-08 Revised:2020-11-24 Online:2021-07-08 Published:2021-07-26
  • Contact: Huang Junxing E-mail:hjxtz@sina.cn
  • Supported by:
    Medical Innovation Team of Jiangsu Province of China(CXTDA2017042)

Abstract:

With the development of immunotherapy in clinical application, immunotherapy also takes advantage in esophageal squamous cell carcinoma (ESCC). Immune checkpoint inhibitors such as programmed death-1 (PD-1) and its ligand PD-L1 and cytotoxic T lymphocyte antigen-4 show significant antitumor activity and safety in immunotherapy for patients with advanced ESCC.

Key words: Esophageal neoplasms, Immunotherapy, T-lymphocytes,cytotoxic, Programmed death-1, Immune checkpoint inhibitor