Abstract: Fenofibrate is a common lipidlowing drug activating peroxisome proliferatoractivated receptor alpha (PPRAα). Recent studies have found that fenofibrate possesses anticancer properties. Its specific mechanisms include inhibiting cell metabolism and formation of new tumor vessels, arresting cell circle, weakening cell motility, and inducing cell apoptosis. Those properties are partly independent of PPRAα. Due to its low sideeffects, it′s hopefully to be used as an anticancer adjuvant drug.

Key words: Procetofen, Neoplasms, Apoptosis, Cell cycle