Journal of International Oncology ›› 2019, Vol. 46 ›› Issue (1): 54-56.doi: 10.3760/cma.j.issn.1673-422X.2019.01.012

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Research progress of new antioxidants in urological neoplasms

Song Jiarui1, Zhang Bin1, Yang Zhongwen2, Xu Baocai2, Wang Chao2, Ma Ming2   

  1. 1School of Medicine and Life Sciences, University of JinanShandong Academy of Medical Sciences, Jinan 250062, China; 2Department of Urological Surgery, Jining First People′s Hospital of Shandong Province, Jining 272011, China
  • Received:2018-09-21 Online:2019-01-08 Published:2019-04-03
  • Contact: Ma Ming E-mail:ming_ma66@126.com

Abstract: Antioxidants are important substances in the body against oxidative stress, which can maintain the balance of redox substances by reducing the content of reactive oxygen species in cells. Studies have shown that new antioxidants have significant inhibitory effects on the growth of urological neoplasms by inhibiting tumor cell proliferation, inducing apoptosis, disturbing angiogenesis and metastasis of tumor cells. Antioxidants are of great value in the prevention and treatment of urinary system tumors and are expected to become new antitumor drugs.

Key words: Antioxidants, Reactive oxygen species, Urologic neoplasms