Abstract: There are so many associated genes,proteins and cytokines altering in the genesis and development of breast cancer. It is very important to detect these tumour markers for the diagnose, therapy and prognosis prodicting of breast cancer. In recent years, following by molecular biology development, the detection items on associated genes and proteins of breast cancer have been carried out one after another, such as ER,PR,HER-2,p53 and so on. However, these detection contents are not identical by each other from different areas and hospitals, without unified standard.

Key words: Breast neoplasms, Tumor markers, biological, Genes, neoplasm