Abstract: miR-205 is differentially expressed in tumor tissues and is closely related to tumorigenesis and tumor metastasis. miR-205 can regulate the biological behaviors of tumor cells such as cell proliferation, differentiation, in situ invasion and distant metastasis by posttranscriptional regulation through binding to targeted genes. Additionally, further research of miR-205 may be helpful for tumor diagnosis, targeted therapy and prognosis.

Key words: microRNAs, Neoplasms, Biological markers