Journal of International Oncology ›› 2025, Vol. 52 ›› Issue (6): 337-342.doi: 10.3760/cma.j.cn371439-20250406-00058

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Research progress on nasopharyngeal carcinoma in children and adolescents

Zhang Yanping1, Xue Jincai2, Xin Yuanchun1, Liu Qinjiang2, Dong Fang1()   

  1. 1Department of Radiation Oncology, Gansu Provincial Cancer Hospital, Lanzhou 730050, China
    2Department of Head and Neck Surgery, Gansu Provincial Cancer Hospital, Lanzhou 730050, China
  • Received:2025-04-06 Revised:2025-05-08 Online:2025-06-08 Published:2025-06-26
  • Contact: Dong Fang E-mail:dfpaulinekeyan@163.com
  • Supported by:
    Science and Technology Program of Gansu Province of China(24JRRA695)

Abstract:

Nasopharyngeal carcinoma is rare in children and adolescents, but the prognosis is relatively good. More and more studies focus on the growth and development, as well as the quality of life of patients after treatment. Certain progress has been made in the research of nasopharyngeal carcinoma in children and adolescents, covering multiple aspects such as etiology, clinical characteristics, treatment regimens and prognosis. The factors causing nasopharyngeal carcinoma include viral infection, genetic susceptibility and environmental factors, etc. The main treatment methods are radiotherapy, chemotherapy, targeted therapy, immunotherapy and surgery. In addition, traditional Chinese medicine has also shown its unique efficacy and potential in the adjuvant therapy of nasopharyngeal carcinoma, providing more treatment options for patients. Further exploration of the factors influencing the occurrence of nasopharyngeal carcinoma in children and adolescents, and analysis of the effects and applications of different treatment methods, can provide new perspectives and references for future research.

Key words: Nasopharyngeal neoplasms, Child, Adolescent, Therapy