Journal of International Oncology ›› 2022, Vol. 49 ›› Issue (4): 247-251.doi: 10.3760/cma.j.cn371439-20220208-00045

• Reviews • Previous Articles     Next Articles

Application of microbiota in the early diagnosis and adjunctive treatment of lung cancer

Gao Min, Feng Jing, Wang Li, Zhong Hai, Wen Yuting, Wan Bing, Zhang Xiuwei()   

  1. Department of Respiratory and Critical Care Medicine, Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China
  • Received:2022-02-08 Revised:2022-03-21 Online:2022-04-08 Published:2022-05-11
  • Contact: Zhang Xiuwei E-mail:zhangxiuweiywy@126.com
  • Supported by:
    Special Plan of Medicine and Technology Development of Nanjing of China(YKK20191)

Abstract:

Drug-resistance and adverse reaction in the treatment of lung cancer patients are still a difficult problem in modern medicine. Studies have indicated that the abundance,diversity and metabolites of intestinal and pulmonary microbiota can be used to assist in the early diagnosis and monitoring the prognosis of lung cancer. Meanwhile, as combined modality therapies, intestinal microbiota combined with chemotherapy, immunotherapy and targeted therapy can enhance therapeutic effect and reduce adverse reaction. Microbiota exhibits an extensive application prospect in the diagnosis and treatment of lung cancer.

Key words: Microbiota, Early diagnosis, Lung neoplasms, Combined modality therapy