Research progress of fibrinogen, NLR and F-NLR grading in gastric cancer

doi:10.3760/cma.j.cn371439-20201230-00083

Abstract

Abstract:

Multiple markers that related to gastric cancer has been widely used in clinical, to predict its occurrence, development and prognosis. Serum level of fibrinogen (FIB) and neutrophil to lymphocytes ratio (NLR) respectively as representative indicators of coagulation system and inflammation, can predict the prognosis of patients with gastric cancer and survival time. The rise of fibrinogen is associated with enhanced capacity of the gastric tumor cells proliferation, invasion and migration. High NLR is associated with significantly induced survival of patients with gastric cancer. The combination of fibrinogen and NLR (F-NLR) combines the advantages of each individual indicator in predicting the occurrence, development and prognosis of cancer. It has shown a great prognostic potential in gastric cancer, and can be widely applied in prospect.

Key words: Stomach neoplasms, Fibrinogen, Prognosis, Neutrophil to lymphocyte ratio

Yang Yinjing, Li Guixiang, Tang Min. Research progress of fibrinogen, NLR and F-NLR grading in gastric cancer[J]. Journal of International Oncology, 2021, 48(7): 433-435.

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