国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (11): 801-804.doi: 10.3760/cma.j.issn.1673422X.2014.11.001

• 综述 •    下一篇

常见恶性肿瘤侧群细胞的研究进展

朱超, 钱军   

  1. 蚌埠医学院第一附属医院肿瘤外三科
  • 出版日期:2014-12-03 发布日期:2015-01-20
  • 通讯作者: 钱军,Email: qianjun215036@sina.com
  • 基金资助:

    国家自然科学基金(8117386)

Side population cells of common tumor

Chao, Qian Jun   

  1.  Third Department of Oncological Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, China
  • Online:2014-12-03 Published:2015-01-20
  • Contact: Qian Jun, Email: qianjun215036@sina.com

摘要: 侧群细胞(SP)是指利用荧光染料Hoechst33342外排特性而筛选出来的细胞群体。SP具有肿瘤干细胞特性,在肿瘤的发生、发展中发挥极其重要的作用。目前国内外对于各类常见恶性肿瘤SP都进行了较为广泛的研究。对SP的研究可为肿瘤的诊断和治疗提供新的思路和方法。

关键词: 肿瘤, 肿瘤干细胞, 侧群细胞

Abstract: Side population cells (SPs) are selected by the efflux features of fluorescent dye Hoechst33342. SPs have the characteristics of cancer stem cells, and play an extremely important role in the occurrence and development of tumors. At present, the SPs in common types of malignant tumor have been studied extensively at home and abroad. The study of SPs may shed some light on the diagnosis and treatment of cancer.

Key words: Neoplasms, Neoplastic stem cells, Side population cells