循环肿瘤细胞株的建立

doi:10.3760/cma.j.issn.1673422X.2014.11.002

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (11): 805-807.doi: 10.3760/cma.j.issn.1673422X.2014.11.002

循环肿瘤细胞株的建立

王焕昇, 李庞, 李胜

山东省肿瘤医院泌尿外科

出版日期:2014-12-03 发布日期:2015-01-20
通讯作者: 李胜，Email: drlisheng@sohu.com
基金资助:
国家重点基础研究发展计划（2011CB504302）

Establishment of circulating tumor cell linesWang

WANG Huan-Sheng, LI Pang, LI Sheng

Department of Urology, Shandong Tumor Hospital, Ji′nan 250117, China

Online:2014-12-03 Published:2015-01-20
Contact: Li Sheng, Email: drlisheng@sohu.com

摘要/Abstract

摘要： 循环肿瘤细胞(CTC)具有的特异性（上皮间质转化、与骨髓来源细胞的融合、抗失巢凋亡）决定了将其作为原代目标进行培养的必要性，所培养出的细胞株将为进一步研究恶性肿瘤的转移机制提供良好的物质基础，为患者的靶向治疗提供个体化的新方向。

关键词: 肿瘤循环细胞, 细胞培养技术, 细胞系, 肿瘤

Abstract: Corresponding author【Abstract】The specificity of circulating tumor cell (CTC) such as epithelialmesenchymal transition, fusion of bone marrowderived cells, resistance anoikis determines the necessity of cell cultivating. The produced cell lines can provide good material basis for further research of malignant tumor metastasis, also provide individualized targeted therapy for patients with a new direction.

Key words: Neoplasm circulating cells, Cell culture techniques, Cell line, tumor

王焕昇, 李庞, 李胜. 循环肿瘤细胞株的建立[J]. 国际肿瘤学杂志, 2014, 41(11): 805-807.

WANG Huan-Sheng, LI Pang, LI Sheng. Establishment of circulating tumor cell linesWang[J]. Journal of International Oncology, 2014, 41(11): 805-807.

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循环肿瘤细胞株的建立

Establishment of circulating tumor cell linesWang

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