国际肿瘤学杂志

国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (11): 841-844.doi: 10.3760/cma.j.issn.1673422X.2015.11.012

• 综述 • 上一篇    下一篇

肿瘤细胞弥散机制及循环肿瘤细胞的检测和临床应用

倪婷,王玉东   

  1. 200030上海交通大学医学院附属国际和平妇幼保健院妇科
  • 出版日期:2015-11-08 发布日期:2015-09-30
  • 通讯作者: 王玉东，Email:owangyudong@126.com E-mail:owangyudong@126.com
  • 基金资助:

    国家自然科学基金（81172477）；上海市科学技术委员会科研计划（11ZR1440800）；上海市卫生和计划生育委员会科研课题（XBR2013097）

Dissemination, detection and clinical use of circulating tumor cell

Ni Ting, Wang Yudong.   

  1. Department of Gynecology, International Peace Maternal and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2015-11-08 Published:2015-09-30
  • Contact: Wang Yudong E-mail:owangyudong@126.com

PDF

1260

摘要： 循环肿瘤细胞（CTC）介导了多种肿瘤的远处转移,通过不同的富集和分离手段检测CTC，对临床预后评估、药效监测以及个体化治疗方案制定均有重要作用。随着研究的深入，CTC检测将有可能成为肿瘤治疗方案制定的常规检查。

关键词: 肿瘤循环细胞, 肿瘤转移, 检测, 治疗

Abstract: Circulating tumor cells (CTCs) mediate distant metastases of many kinds of cancer. The detection and characterization of CTC through different enrichment and isolation methods play important roles in assessing of prognosis, monitoring of therapy response and decision making of personalized treatment. With the development of continued research, detection of CTC may become a routine test for therapeutic decision making of cancer.

Key words: Neoplasm circulating cells, Neoplasm metastasis, Detection, Therapy