国际肿瘤学杂志

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (10): 760-763.doi: １０．３７６０／ｃｍａ．ｊ．ｉｓｓｎ．１６７３４２２Ｘ．２０１４．１０．０１３

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Ｈｅｒ２基因与乳腺癌靶向治疗

黄灵潇,姚文秀   

  1. ４０００１６重庆医科大学临床学院
  • 出版日期:2014-10-29 发布日期:2014-10-11
  • 通讯作者: 姚文秀，Ｅｍａｉｌ：ｙｗｘｈｌｘ＠ｓｉｎａ．ｃｏｍ E-mail:ｙｗｘｈｌｘ＠ｓｉｎａ．ｃｏｍ

Her2 gene and breast cancer targeted therapy

 HUANG  Ling-Xiao, YAO  Wen-Xiu   

  1. Clinical College, Chongqing Medical University, Chongqing 400016, China
  • Online:2014-10-29 Published:2014-10-11
  • Contact: ＹａｏＷｅｎｘｉｕ E-mail:ｙｗｘｈｌｘ＠ｓｉｎａ．ｃｏｍ

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摘要： 近年来随着肿瘤分子生物学技术的发展，分子靶向药物治疗已成为众多学者关注的热点 领域，对乳腺癌的治疗策略产生了重大影响。其中，人表皮生长因子受体２（Ｈｅｒ２）已证实为一个有效 的分子靶向治疗的靶标，针对乳腺癌 Ｈｅｒ２的分子靶向治疗成为近来继化疗和内分泌治疗后又一重要 的治疗手段。

关键词: 乳腺肿瘤, 靶向治疗, Ｈｅｒ２基因

Abstract: In recent years, with the development of tumor molecular biology technology, molecular targeted therapy has become a study hotspot, which plays a significant role on breast cancer treatment strategy. Among them, the human epidermal growth factor receptor2 (Her2) has been proven as an effective molecular target. So molecular targeted therapy of breast cancer become another important treatment except chemotherapy and endocrine therapy.

Key words: Breast neoplasms, Targeted therapy, Her2 gene