国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (3): 196-200.

• 综述 • 上一篇    下一篇

天然活性产物的放射增敏作用

王娟, 金问森   

  1. 230032 合肥,安徽医科大学核医学教研室
  • 出版日期:2012-03-08 发布日期:2012-02-24
  • 基金资助:

    博士后科学基金面上资助项目(20100470822);安徽省教育厅重点科研项目(KJ2010A189

Radiosensitizing effect of natural active product on tumor

WANG  Juan, JIN  Wen-Sen   

  1. Teaching & Research Section of Nuclear Medicine, An-hui Medical University, Hefei 230032, China
  • Online:2012-03-08 Published:2012-02-24

摘要: 天然产物中存在大量具有放射增敏作用的活性物质,这些物质能够通过不同的作用机制,提高肿瘤的放射敏感性,达到增强放疗效果之目的。探讨放射增敏作用的机制,对具有发展成为放射增敏药物潜力的天然化合物进行分类,可为天然放射增敏剂的进一步研发提供一定思路。

关键词: color: black, font-family: 宋体, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-bidi-font-family: 'Times New Roman', mso-font-kerning: 1.0pt">辐射增敏药, 肿瘤, 放射疗法

Abstract: It has been indicated that there are a large number of natural active compounds generating the radiosensitizing effect on tumor. According to diverse molecular mechanism, these compounds may enhance the radiotherapeutic efficacy via enhancing the radiosensitivity of tumor. Studying the radiosensitization mechanism and classifying the natural compounds with the potentiality of development into clinical radiosensitizers can provide certain ideas for further research and development of natural radiosensitizers.

Key words: color: black, font-family: "Times New Roman", mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-font-kerning: 1.0pt">Radiation-sensitizing agents, color: black, font-family: "Times New Roman", mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-font-kerning: 1.0pt">Neoplasms, color: black, font-family: "Times New Roman", mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-font-kerning: 1.0pt">Radiotherapy