国际肿瘤学杂志

国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (3): 193-196.

• 综述 • 上一篇    下一篇

纳米粒载体在光动力治疗肿瘤中的应用

石磊,王秀丽,王宏伟   

  1. 200050 安徽医科大学上海皮肤病性病临床学院暨上海市皮肤病医院
  • 出版日期:2012-03-08 发布日期:2012-02-24
  • 基金资助:

    上海市自然科学基金项目（11ZR1432800）

Application of nanoparticle vectors in photodynamic therapy of tumors

SHI  Lei, WANG  Xiu-Li, WANG  Hong-Wei   

  1. SHI Lei, WANG Xiu-li, WANG Hong-wei. Shanghai Skin Disease Hospital ＆ Shanghai Clinical Institute of Skin and Venereal Disease, Anhui Medical University, Shanghai 200050, China
  • Online:2012-03-08 Published:2012-02-24

PDF

2827

被引次数

8

摘要： 近年来，纳米粒载体技术被广泛应用到光动力治疗肿瘤中，可通过多种途径增强光敏剂的稳定性，提高光动力治疗的肿瘤靶向性、作用深度、单态氧产出率。依靠纳米粒，光动力治疗还可与其他治疗方法联合应用。纳米粒载体技术应用到光动力治疗中可以提高治疗肿瘤的效果、减少不良反应、扩大适用范围，是一项极具发展前景的新技术。

关键词: color: black, font-family: 宋体, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-bidi-font-family: 'Times New Roman', mso-font-kerning: 1.0pt">纳米粒子, 光化学疗法, 肿瘤, 光敏感药

Abstract: For the past few years, with the extensive application of nanoparticle technology in photodynamic therapy (PDT) of cancers, there have been some improvements of the stability of photosensitizers, the tumor targeting, the working depth and the yield of singlet oxygen by a variety of ways. Furthermore, with nanoparticle, PDT also can be combined with some other treatments together. Finally, the use of nanoparticle vectors for PDT is a novel and promising approach which might improve the efficiency of photodynamic therapy for tumors, overcome many adverse effects and increase the indications of PDT.

Key words: color: black">Nanoparticles, color: black">Photochemotherapy, Neoplasms, text-decoration: none, text-underline: none">Photosensitizing agents