IL-35、IL-39、IL-27在肿瘤微环境中的调节作用

doi:10.3760/cma.j.cn371439-20200722-00042

摘要/Abstract

摘要：

白细胞介素(IL)家族能直接或间接地刺激肿瘤细胞增殖、存活和扩散,并进一步塑造肿瘤微环境,从而在一定程度上影响肿瘤的生长与转化。研究发现IL-12家族的新成员IL-35、IL-39、IL-27在多种肿瘤中发挥相关的特异性免疫功能,可能是肿瘤研究的重要靶向分子。

关键词: 肿瘤微环境, 免疫, 细胞因子

Abstract:

The interleukin family can directly or indirectly stimulates the proliferation, survival and diffusion of tumor cells, and further shapes the tumor microenvironment, thus affecting the tumor growth and transformation to a certain extent. Studies show that the new numbers of IL-12 family, IL-35, IL-39 and IL-27, play the relevant specific immune functions in a variety of tumors, which may be important target molecules for tumors research.

Key words: Tumor microenvironment, Immunity, Cytokines

刘赛赛, 袁东亚. IL-35、IL-39、IL-27在肿瘤微环境中的调节作用[J]. 国际肿瘤学杂志, 2021, 48(4): 212-215.

Liu Saisai, Yuan Dongya. Regulation of IL-35, IL-39 and IL-27 in tumor microenvironment[J]. Journal of International Oncology, 2021, 48(4): 212-215.

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