国际肿瘤学杂志

国际肿瘤学杂志 ›› 2019, Vol. 46 ›› Issue (11): 692-694.doi: 10.3760/cma.j.issn.1673-422X.2019.11.010

• 综述 • 上一篇    下一篇

CNPY2在肿瘤中的表达及作用

屈振杰1崔琴2   

  1. 1内蒙古包钢医院肿瘤内科，包头014010； 2内蒙古包钢医院消化内科，包头014010
  • 出版日期:2019-11-08 发布日期:2019-12-26
  • 通讯作者: 崔琴 E-mail:cuiqin2010luck@126.com

Expression and function of CNPY2 in tumors

Qu Zhenjie1, Cui Qin2   

  1. 1Department of Medical Oncology, Inner Mongolia Baotou Steel Hospital, Baotou 014010, China; 2Department of Gastroenterology, Inner Mongolia Baotou Steel Hospital, Baotou 014010, China
  • Online:2019-11-08 Published:2019-12-26
  • Contact: Cui Qin E-mail:cuiqin2010luck@126.com

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摘要： 肿瘤在生长过程中为满足营养供给，需形成大量新生血管，目前抗肿瘤血管生成是抗肿瘤药物研发的重要方向之一。CNPY2是一种新型的分泌型促血管生成因子，通过促血管生成作用参与肿瘤的发生发展。CNPY2在多种肿瘤中异常表达，可能成为肿瘤诊断和治疗的新靶点。

关键词: 肿瘤, CNPY2

Abstract: In order to satisfy the nutritional supply, neovascularization is needed in the growth of tumors. At present, anti-angiogenesis is one of the important directions in the research and development of anti-cancer drugs. CNPY2 is a new secretory angiogenic factor, which may participate in the occurrence and deve-lopment of tumors by promoting angiogenesis. CNPY2 is abnormally expressed in a variety of tumors, and it may be a new target for diagnosis and treatment of tumors.

Key words: Neoplasms, CNPY2