国际肿瘤学杂志

国际肿瘤学杂志 ›› 2018, Vol. 45 ›› Issue (4): 226-228.doi: 10.3760/cma.j.issn.1673-422X.2018.04.009

• 综述 • 上一篇    下一篇

肿瘤组织中微小RNA-335的表达与预后的关系

徐晓彦,吴银洁,尹玲,徐飞,于壮   

  1. 266000 青岛大学附属医院肿瘤化疗科
  • 出版日期:2018-04-08 发布日期:2018-05-16
  • 通讯作者: 于壮，Email： yuzhuang2002@163.com E-mail:yuzhuang2002@163.com
  • 基金资助:

    山东省自然科学基金（ZR2017MH062）

Relationship between microRNA-335 expression and prognosis in tumor tissue

Xu Xiaoyan, Wu Yinjie, Yin Ling, Xu Fei, Yu Zhuang   

  1. Department of Tumor Chemotherapy, Affiliated Hospital of Qingdao University, Qingdao 266000, China
  • Online:2018-04-08 Published:2018-05-16
  • Contact: Yu Zhuang, Email: yuzhuang2002@163.com E-mail:yuzhuang2002@163.com
  • Supported by:

    Natural Science Foundation of Shandong Province of China （ZR2017MH062）

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被引次数

2

摘要： 微小RNA-335（miR-335）的低表达在许多肿瘤中提示预后不良，如胃癌、乳腺癌、肺癌等一系列实体肿瘤。低表达的miR-335可促进肿瘤转移和进展，并且与组织学分级、淋巴结转移、肿瘤分期显著相关，为肿瘤的诊治提供了新的思路。

关键词: 微RNAs, 肿瘤, 预后

Abstract: The low expression of microRNA-335 (miR-335) indicates poor prognosis in many types of cancer, such as gastric cancer, breast cancer, lung cancer and other solid tumors. The low expression of miR-335 can promote tumor metastasis and progression, and is associated with histological grading, lymph node metastasis and tumor staging, which  provids a new way of thinking for the diagnosis and treatment of tumors.

Key words: MicroRNAs, Neoplasms, Prognosis