[1] Du WQ, Zheng JN, Pei DS. The diverse oncogenic and tumor suppressor roles of saltinducible kinase (SIK) in cancer[J]. Expert Opin Ther Targets, 2016, 20(4): 477-485. DOI: 10.1517/14728222.2016.1101452.
[2] Finsterwald C, Carrard A, Martin JL. Role of saltinducible kinase 1 in the activation of MEF2dependent transcription by BDNF[J]. PLoS One, 2013, 8(1): e54545. DOI: 10.1371/journal.pone.0054545.
[3] Nixon M, StewartFitzgibbon R, Fu J, et al. Skeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity[J]. Mol Metab, 2016, 5(1): 34-46. DOI: 10.1016/j.molmet.2015.10.004.
[4] Kim MJ, Park SK, Lee JH, et al. Saltinducible kinase 1 terminates cAMP signaling by an evolutionarily conserved negativefeedback loop in βcells[J]. Diabetes, 2015, 64(9): 31893202. DOI: 10.2337/db141240.
[5] Bertorello AM, Pires N, Igreja B, et al. Increased arterial blood pressure and vascular remodeling in mice lacking salt inducible kinase 1 (SIK1)[J]. Circ Res, 2015, 116(4): 642652. DOI: 10.1161/CIRCRESAHA.116.304529.
[6] Eneling K, Chen J, Welch LC, et al. Saltinducible kinase 1 is present in lung alveolar epithelial cells and regulates active sodium transport[J]. Biochem Biophys Res Commun, 2011, 409(1): 28-33. DOI: 10.1016/j.bbrc.2011.04.100.
[7] Qu C, He D, Lu X, et al. Saltinducible kinase (SIK1) regulates HCC progression and WNT/βcatenin activation[J]. J Hepatol, 2016, 64(5): 1076-1089. DOI: 10.1016/j.jhep.2016.01.005.
[8] Qu C, Qu Y. Downregulation of saltinducible kinase 1 (SIK1) is mediated by RNF2 in hepatocarcinogenesis[J]. Oncotarget, 2017, 8(2): 31443155. DOI: 10.18632/oncotarget.13673.
[9] Zou YF, Xie CW, Yang SX, et al. AMPK activators suppress breast cancer cell growth by inhibiting DVL3facilitated Wnt/βcatenin signaling pathway activity[J]. Mol Med Rep, 2017, 15(2): 899-907. DOI: 10.3892/mmr.2016.6094.
[10] Chen Y, Huang Q, Zhou H, et al. Inhibition of canonical WNT/β-catenin signaling is involved in leflunomide (LEF)mediated cytotoxic effects on renal carcinoma cells[J]. Oncotarget, 2016, 7(31): 50401-50416. DOI: 10.18632/oncotarget.10409.
[11] Fan D, Ren B, Yang X, et al. Upregulation of miR5015p activates the wnt/betacatenin signaling pathway and enhances stem celllike phenotype in gastric cancer[J]. J Exp Clin Cancer Res, 2016, 35(1): 177. DOI: 10.1186/s13046-016-0432-x.
[12] Klose J, Eissele J, Volz C, et al. Salinomycin inhibits metastatic colorectal cancer growth and interferes with Wnt/betacatenin signaling in CD133+ human colorectal cancer cells[J]. BMC Cancer, 2016, 16(1): 896. DOI: 10.1186/s12885-016-2879-8.
[13] Liu Y, Gao S, Chen X, et al. Overexpression of miR203 sensitizes paclitaxel (Taxol)resistant colorectal cancer cells through targeting the saltinducible kinase 2 (SIK2)[J]. Tumour Biol, 2016, 37(9): 1223112239. DOI: 10.1007/s13277-016-5066-2.
[14] Miranda F, Mannion D, Liu S, et al. Saltinducible kinase 2 couples ovarian cancer cell metabolism with survival at the adipocyterich metastatic niche[J]. Cancer Cell, 2016, 30(2): 273289. DOI: 10.1016/j.ccell.2016.06.020.
[15] Simard EP, Ward EM, Siegel R, et al. Cancers with increasing incidence trends in the United States: 1999 through 2008[J]. CA Cancer J Clin, 2012, 62(2): 118-128. DOI: 10.1016/j.juro.2012.06.090.
[16] Ren ZG, Dong SX, Han P, et al. miR203 promotes proliferation, migration and invasion by degrading SIK1 in pancreatic cancer[J]. Oncol Rep, 2016, 35(3): 1365-1374. DOI: 10.3892/or.2015.4534.
[17] 魏永永, 侯静, 唐文如, 等. p53与Ras协同及其在肿瘤发生中的作用[J]. 遗传, 2012, 34(12): 15131521. DOI: 10.3724/SP.J.1005.2012.01513.
[18] Witte D, Zeeh F, Gdeken T, et al. Proteinaseactivated receptor 2 is a novel regulator of TGFβ signaling in pancreatic cancer[J]. J Clin Med, 2016, 5(12): 111. DOI: 10.3390/jcm5120111.
[19] Demagny H, De Robertis EM. Point mutations in the tumor suppressor Smad4/DPC4 enhance its phosphorylation by GSK3 and reversibly inactivate TGFbeta signaling[J]. Mol Cell Oncol, 2016, 3(1): e1025181. DOI: 10.1080/23723556.2015.1025181.
[20] Steigedal TS, Prestvik WS, Selvik LK, et al. Gastrininduced proliferation involves MEK partner 1 (MP1)[J]. In Vitro Cell Dev Biol Anim, 2013, 49(3): 162-169. DOI: 10.1007/s1162601395882.
[21] Selvik LK, Rao S, Steigedal TS, et al. Saltinducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells[J]. PLoS One, 2014, 9(11): e112485. DOI: 10.1371/journal.pone.0112485.
[22] Chen JL, Chen F, Zhang TT, et al. Suppression of SIK1 by miR141 in human ovarian cancer cell lines and tissues[J]. Int J Mol Med, 2016, 37(6): 1601-1610. DOI: 10.3892/ijmm.2016.2553.
[23] Xu J, Wu W, Wang J, et al. miR367 promotes the proliferation and invasion of nonsmall cell lung cancer via targeting FBXW7[J]. Oncol Rep, 2017, 37(2): 1052-1058. DOI: 10.3892/or.2016.5314.
[24] Meng X, Lu P, Fan Q. miR367 promotes proliferation and invasion of hepatocellular carcinoma cells by negatively regulating PTEN[J]. Biochem Biophys Res Commun, 2016, 470(1): 187191. DOI: 10.1016/j.bbrc.2016.01.025.
[25] Chen W, Zheng R, Zeng H, et al. The updated incidences and mortalities of major cancers in China, 2011[J]. Chin J Cancer, 2015, 34(11): 502-507. DOI: 10.1186/s40880-015-0042-6.
[26] Yao YH, Cui Y, Qiu XN, et al. Attenuated LKB1SIK1 signaling promotes epithelialmesenchymal transition and radioresistance of nonsmall cell lung cancer cells[J]. Chin J Cancer, 2016, 35: 50. DOI: 10.1186/s4088001601133.
[27] Shaw RJ. Tumor suppression by LKB1: SIKness prevents metastasis[J]. Sci Signal, 2009, 2(86): e55. DOI: 10.1126/scisignal.286pe55.
[28] Bai L, Lin G, Sun L, et al. Upregulation of SIRT6 predicts poor prognosis and promotes metastasis of nonsmall cell lung cancer via the ERK1/2/MMP9 pathway[J]. Oncotarget, 2016, 7(26): 40377-40386. DOI: 10.18632/oncotarget.9750.
[29] Yang N, Cui H, Han F, et al. Paeoniflorin inhibits human pancreatic cancer cell apoptosis via suppression of MMP9 and ERK signaling[J]. Oncol Lett, 2016, 12(2): 1471-1476. DOI: 10.3892/ol.2016.4761. |