国际肿瘤学杂志

国际肿瘤学杂志 ›› 2016, Vol. 43 ›› Issue (3): 201-203.doi: 10.3760/cma.j.issn.1673-422X.2016.03.010

• 综述 • 上一篇    下一篇

鼻咽癌调强放疗中靶区及危及器官的体积和剂量变化

满宪凤,范廷勇   

  1. 250022 济南大学 山东省医学科学院医学与生命科学学院(满宪凤)；山东省肿瘤医院放疗科（满宪凤、范廷勇）
  • 出版日期:2016-03-08 发布日期:2016-02-03
  • 通讯作者: 范廷勇，Email： fty681105@sohu.com E-mail:fty681105@sohu.com

Changes of volume and dose in target volume and organ at risk for nasopharyngeal carcinoma during intensity modulated radiotherapy

Man Xianfeng， Fan Tingyong   

  1. School of Medicine and Life Sciences, University of Ji′nanShandong Academy of Medical Science, Ji′nan 250022, China; Department of Radiation Oncology, Shandong Cancer Hospital and Institution, Ji′nan 250117, China
  • Online:2016-03-08 Published:2016-02-03
  • Contact: Fan Tingyong, Email: fty681105@sohu.com E-mail:fty681105@sohu.com

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摘要： 目前调强放疗是鼻咽癌的主要治疗手段。在6～7周的疗程中，临床大部分医师均使用初始制定的放疗计划。研究表明，由于原发肿瘤和转移淋巴结的缩小以及体质量下降导致的正常组织和体表轮廓的收缩，这些有意义的变化将影响靶区及危及器官的剂量分布，从而影响部分患者的治疗疗效。鼻咽癌调强放疗期间复位并进行靶区修改很有必要。

关键词: 鼻咽肿瘤, 放射疗法, 调强适形, 靶区体积, 危及器官

Abstract: At present, intensity modulated radiation therapy has been the main treatment of nasopharyngeal carcinoma. In the course of 6~7 weeks, most physicians use the initial formulation of the radiotherapy plan. Studies have indicated that the reduction of primary tumor and lymph nodes, as well as the reduction of normal tissue and body surface profile due to the weight loss, will affect the dose distribution of the target and the organs at risk, so as to influence the therapeutic effect of some patients. Therefore, it is necessary to reset and modify the target volumes during the radiotherapy for nasopharyngeal carcinoma.

Key words: Nasopharyngeal neoplasms, Radiotherapy, intensity-modulated, Target volumes, Organs at risk