国际肿瘤学杂志

国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (8): 616-618.doi: 10.3760/cma.j.issn.1673422X.2015.08.015

• 综述 • 上一篇    下一篇

 肿瘤的精准治疗

张百红,岳红云   

  1. 730050 兰州军区兰州总医院肿瘤科（张百红）,眼科（岳红云）
  • 出版日期:2015-08-08 发布日期:2015-06-29
  • 通讯作者: 张百红，Email：bhzhang1999@126.com E-mail:bhzhang1999@126.com
  • 基金资助:

    甘肃省自然科学基金（1308RJZA181）

Cancer precision therapeutics

 ZHANG  Bai-Hong, YUE  Hong-Yun   

  1. Department of Oncology, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, China
  • Online:2015-08-08 Published:2015-06-29
  • Contact: ZHANG Bai-Hong E-mail:bhzhang1999@126.com

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摘要： 肿瘤的精准治疗指基于高通量分子技术获得肿瘤分子图谱和分类并指导肿瘤治疗的医学模式。肿瘤精准治疗得益于二代测序技术的进步和分子靶向药物的问世。精确靶标、多靶向联合和实时监控是实现精准治疗的关键。

关键词: 肿瘤, 治疗, 药物学

Abstract: Cancer precision therapeutics is defined as a therapy strategy based on molecular profiles and classifiers generated from highthroughput molecular assays. Precision therapeutics in oncology is becoming reality thanks to the nextgeneration sequencing and cancer targeted agents. Selecting optimal targets, identifying appropriate combinations of therapies and realtime monitoring of tumor evolution may be critical for practicing precision therapeutics.

Key words: Neoplasms, Therapy, Pharmacology