脂肪因子与结直肠癌

doi:10.3760/cma.j.issn.1673-422X.2015.01.018

国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (1): 67-70.doi: 10.3760/cma.j.issn.1673-422X.2015.01.018

脂肪因子与结直肠癌

陈燕, 陈明卫

230032合肥，安徽医科大学第一附属医院内分泌科

收稿日期:2014-06-18 修回日期:2014-10-08 出版日期:2015-01-08 发布日期:2015-01-07
通讯作者: 陈明卫 E-mail:chmw1@163.com
基金资助:
中华医学会临床医学科研专项（12020320322）；安徽省科技计划（1206c0805034）

Adipokines and colorectal cancer

Chen Yan, Chen Mingwei

Department of Endocrinology, First Affiliated Hospital of Anhui Medcial University, Hefei 230032, China

Received:2014-06-18 Revised:2014-10-08 Online:2015-01-08 Published:2015-01-07
Contact: Chen Mingwei E-mail:chmw1@163.com

摘要/Abstract

摘要： 脂联素、瘦素、网膜素、内脂素均为脂肪组织细胞分泌的脂肪因子，与肥胖、胰岛素抵抗密切相关。研究发现上述脂肪因子也与结直肠癌的发生发展密切相关，有望成为结直肠癌临床诊断以及预后判断的生物学标志物。目前关于脂肪因子如何诱发结直肠癌的机制尚不清楚，仍需开展深入的研究。

关键词: 脂肪因子类, 结直肠肿瘤, 肥胖症

Abstract: Adipocytokines included adiponectin, leptin, omentin and visfatin are secreted by adipocytes and closely associated with obesity and insulin resistance. Many studies find that these adipocytokines are correlated with the occurrence and development of colorectal cancer, and may be promising biomarkers with respect to clinical diagnosis and prognosis of colorectal cancer. At present, the occurrence mechanisms of colorectal cancer induced by adipocytokines are unclear and needed to be extensively explored.

Key words: Adipokines, Colorectal neoplasms, Obesity

陈燕, 陈明卫. 脂肪因子与结直肠癌[J]. 国际肿瘤学杂志, 2015, 42(1): 67-70.

Chen Yan, Chen Mingwei. Adipokines and colorectal cancer[J]. Journal of International Oncology, 2015, 42(1): 67-70.

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脂肪因子与结直肠癌

Adipokines and colorectal cancer

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