国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (8): 561-564.doi: 10.3760/cma.j.issn.1673-422X.2014.08.001

• 综述 •    下一篇

再生基因Ⅳ在肿瘤中的作用及临床应用

吴怡晨, 应莉莎, 凌志强   

  1. 310022杭州,浙江省肿瘤医院肿瘤研究所
  • 收稿日期:2013-11-28 修回日期:2014-03-15 出版日期:2014-08-15 发布日期:2014-08-14
  • 通讯作者: 应莉莎,E-mail:ilonas@163.com E-mail:ilonas@163.com
  • 基金资助:

    浙江省自然科学基金(LQ13H160017)

Roles of RegⅣ in neoplasms and clinical applications

Wu  Yichen, Ying  Lisha, Ling  Zhiqiang   

  1. Cancer Research Institute, Zhejiang Province Cancer Hospital, Hangzhou 310022, China
  • Received:2013-11-28 Revised:2014-03-15 Online:2014-08-15 Published:2014-08-14
  • Contact: Ying Lisha E-mail:ilonas@163.com

摘要: 再生基因Ⅳ(RegⅣ)是再生基因家族的一员,与消化系统细胞的增殖和分化相关。RegⅣ与肿瘤的发生、发展,肿瘤细胞的增殖、侵袭以及抗凋亡等密切相关,可能是肿瘤靶向治疗潜在的分子靶标。

关键词: 肿瘤, 细胞增殖, 治疗, 再生基因Ⅳ

Abstract: As a member of regenerating isletderived family, regenerating isletderived type Ⅳ (RegⅣ) is involved in cell proliferation and differentiation.  RegⅣ is closely related to the occurrence and development of tumor, tumor cell proliferation and invasion and antiapoptosis, and it may be a potential molecular target of targeting therapy in cancer.

Key words: Neoplasms, Cell proliferation, Therapy, RegⅣ