国际肿瘤学杂志

国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (1): 68-71.

• 综述 • 上一篇    下一篇

阿司匹林预防大肠癌的研究进展

徐邓勇, 丁克峰   

  1. 310009杭州，浙江大学医学院附属第二医院肿瘤外科

  • 出版日期:2013-01-08 发布日期:2013-01-15
  • 通讯作者: 丁克峰，E-mail：dingkefeng@126.com E-mail:dingkefeng@126.com
  • 基金资助:

    国家自然科学基金（81071801）浙江省自然科学基金（R2100071）

Aspirin in the prevention of colorectal cancer

XU  Deng-Yong, DING  Ke-Feng   

  1. Department of Surgical Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China

  • Online:2013-01-08 Published:2013-01-15
  • Contact: Corresponding author: Ding Ke-feng，E-mail:dingkefeng@126.com E-mail:dingkefeng@126.com

PDF

1520

被引次数

5

摘要： 大量研究表明阿司匹林及其他的非甾体药物（NSAID）对许多肿瘤有一定的化学预防作用，尤其在大肠癌方面。预防大肠癌，有药物预防性优势。研究发现，阿司匹林对高、中、低危人群的化学预防作用在时间和剂量上有不同程度的差别，对一般风险人群中腺瘤发病率的影响证据较少。

关键词: 结直肠肿瘤, 阿司匹林, 化学预防

Abstract: A large number of studies show that aspirin and other non-steroid anti-inflammatory drugs (NSAID) have chemopreventive effects on several cancer types, and more specifically in colorectal cancer. Aspirin can help prevent colon cancer, which has the specific advantage of drug prophylaxis. Studies found that aspirin play the different roles on high-risk, moderate-risk and low-risk populations in time and dose. There is limited evidence about the influence on incidence of adenoma among the general risk populations.

Key words: Colorectal neoplasms, Aspirin, Chemoprevention