国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (7): 492-497.

• 综述 • 上一篇    下一篇

肿瘤血管生成机制研究进展

耿良,花宝金   

  1. 北京,中国中医科学院广安门医院肿瘤科
  • 出版日期:2012-08-06 发布日期:2012-08-06
  • 通讯作者: 花宝金,E-mail:huabaojin@sohu.com E-mail:huabaojin@sohu.com
  • 基金资助:

    国家自然科学基金资助项目(30973839)

Mechanism of tumor angiogenesis

GENG  Liang, HUA  Bao-Jin   

  1. Department of Oncology, Guang′anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
  • Online:2012-08-06 Published:2012-08-06
  • Contact: HUA Bao-jin, E-mail: huabaojin@sohu.com E-mail:huabaojin@sohu.com

摘要: 肿瘤的进展和转移必须依赖新生血管的支持,为了达到切断肿瘤血氧供应而抑制甚至治愈肿瘤的目的,研究人员在肿瘤血管生成机制方面进行了大量的研究并取得了一些成果。这些成果表明,众多的因素共同参与了肿瘤的血管新生过程,各种因素通过细胞和分子机制相互作用,构成了肿瘤血管新生的复杂调控网络。

关键词: 肿瘤, 血管生成, 调控机制

Abstract: Based on the theory of tumor angiogenesis, the vascular system is necessary for the advance and metastasis of the tumor. To inhibit or even cure the tumor, the researchers all over the world have made a great many of studies on the mechanism of tumor angiogenesis and have acquired some achievements. Based on the findings, a lot of factors are involved in tumor angiogenesis, and they constitute the complex regulating network through interaction at the molecular and cellular level. 

Key words: Neoplasms, Angiogenesis, Regulating mechanism