国际肿瘤学杂志

国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (4): 243-245.

• 综述 •    下一篇

外周血循环RNA与肿瘤诊断

庄珊珊; 方裕森; 陈炯玉   

  1. 汕头大学医学院附属肿瘤医院
  • 出版日期:2012-04-08 发布日期:2012-03-28
  • 通讯作者: 陈炯玉,E-mail:kinyny@21cn.com E-mail:kinyny@21cn.com

Peripheral blood circulating RNA andcancer diagnosis

ZHUANG  Shan-Shan, FANG  Yu-Sen, CHEN  Jiong-Yu   

  1. Department of Laboratory, Cancer Hospital of Shantou University Medical College, Shantou 515041, China
  • Online:2012-04-08 Published:2012-03-28
  • Contact: Corresponding author: CHEN Jiong-yu, E-mail: kinyny@21cn.com E-mail:kinyny@21cn.com

PDF

2039

被引次数

5

摘要： 研究发现外周血循环RNA含量在多种恶性肿瘤患者血清中特异性升高，是潜在的肿瘤诊断的生物学标志和药物治疗靶点。通过分子生物学技术检测肿瘤循环RNA，将为恶性肿瘤的早期诊断与筛查、预后评价和疗效监测提供敏感高效、方便快捷、特异、无创或微创的检测方法。

关键词: 肿瘤, 血液, 核酸类, 诊断

Abstract: Numerous studies found that the content of peripheral blood circulating RNA in various cancer types is aberrant increased, which could be a potential biological diagnostic marker and therapeutic target. Detecting the peripheral blood circulating RNA through the molecular biology technology will provide a sensitive and efficient, convenient, specific, noninvasive and minimally invasive therapy for the early diagnosis and detection, prognosis and therapeutic monitoring of malignant tumor.

Key words: Neoplasms, Blood, Nucleic acids, Diagnosis