国际肿瘤学杂志

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (6): 447-450.doi: 10.3760/cma.j.issn.1673422X.2014.06.014

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青少年胃肠道间质瘤研究进展

朱玉萍, 李德川, 刘卓   

  1. 310022 杭州，浙江省肿瘤医院结直肠肿瘤外科
  • 出版日期:2014-06-08 发布日期:2014-05-08
  • 通讯作者: 李德川 E-mail:dechuanli@126.com
  • 基金资助:

    浙江省医药卫生科技计划项目（2011ZHA002、2013KYB046）

Research progress of gastrointestinal stromal tumor

Zhu Yuping, Li Dechuan, Liu Zhuo.   

  1. Department of Colorectal Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, China 
  • Online:2014-06-08 Published:2014-05-08
  • Contact: Li Dechuan E-mail:dechuanli@126.com

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1255

被引次数

4

摘要： 胃肠道间质瘤是一种胃肠道最常见的间叶组织来源的肿瘤，多见于中老年人，青少年罕见。青少年胃肠间质瘤临床诊断参考成人胃肠间质瘤的诊断标准，更加注重基因诊断。青少年胃肠间质瘤主要依靠外科治疗，对于晚期不可切除的患者根据基因检测结果可考虑伊马替尼或索尼替尼靶向治疗。

关键词: 青少年, 治疗, 胃肠道肿瘤

Abstract: Gastrointestinal stromal tumor is one kind of the most common gastrointestinal tumors derived from the mesenchymal tissue. In most cases, it  occurs in adults, while rarely occurs in adolescents. The clinical diagnosis of pediatric GIST  can refer to the diagnosis standard of adults GIST, but it pays more attention to genetic diagnosis. The main treatment for pediatric GIST is surgery, but for advanced or unresectable patients, we can adopt  imatinib or sutent for targeted therapy according to the results of genetic testing.

Key words: Adolescent, Therapy, Gastrointestinal neoplasms